Title: Car Rental Santa Cruz: Cheap Santa Cruz Car Rental Deals | Expedia.com [Santa Cruz Hotels](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[Santa Cruz Flights](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Vacation Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Vacation-Rental-Destinations)[Santa Cruz Vacations](https://expedia.com/Santa-Cruz.d6297178.Destination-Travel-Guides) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Cruz Car Rentals ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) ## Top destinations to rent a car in Santa Cruz ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide) ![Mountain view in Samaipata, Florida Province of the Santa Cruz Department, Bolivia](https://images.trvl-media.com/place/6200976/99855abd-1497-49bc-91a5-ef76c4e902cb.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.com/Car-Rentals-In-Samaipata.d6200976.Car-Rental-Guide) ![Portrait of a Tobas warrior during carnival called The Devil Dance (La Diablada), Oruro, Bolivia](https://images.trvl-media.com/place/6352296/feec42f5-cbd9-4576-97cc-129e51391796.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Warnes [](https://expedia.com/Car-Rentals-In-Warnes.d6352296.Car-Rental-Guide) ![Catedral da Cidade de Santa Cruz de La Sierra na Bolivia.](https://images.trvl-media.com/place/553248635975872931/1c16d6d1-f5ea-4f81-a5b9-a375e600f045.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Montero [](https://expedia.com/Car-Rentals-In-Montero.d553248635975872931.Car-Rental-Guide) ![Jesuit Mission wall paintings in San Jose de Chiquitos, Bolivia](https://images.trvl-media.com/place/6344854/c34a2d19-1f8b-4361-810e-e1669bf071f5.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Jose de Chiquitos [](https://expedia.com/Car-Rentals-In-San-Jose-De-Chiquitos.d6344854.Car-Rental-Guide) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_6297178) ## Find Santa Cruz Car Rentals Expedia.com makes it easy for you to book your next Santa Cruz car rental. We work with the best car rental companies in Santa Cruz, bringing you discount car rental rates and a wide variety of car rental classes including economy, compact, midsize, full-size, convertible, van, luxury and SUV rentals. Our partner car rental companies in Santa Cruz offer different pick-up and drop-off options. If you are ready to book your Santa Cruz car rental, follow the links on this page to view more information and details on your next short or [long term car rental](https://www.expedia.com/lp/b/car-rental/long-term). Expedia.com offers a wide selection of rental cars in Santa Cruz to meet nearly every need. If you need any special equipment, like a child seat or ski rack, let us know and we will forward your request on to the rental car company. And what's more, when you choose to rent a car from one of our Santa Cruz airport car rental partners you'll be dealing with a rental car company that has made a special commitment to provide Expedia customers with great customer service, a wide choice of top quality cars, and competitive total pricing. ### Expedia.com offers many Santa Cruz rental cars pick up locations Find the best place to get your Santa Cruz airport rental cars by searching tons of pickup locations with Expedia.com --- ## Frequently asked questions ### What happens if I need to cancel my Santa Cruz car reservation? ### How do I find the best car rental deals in Santa Cruz with Expedia? ### What do you need to rent a car in Santa Cruz? ### Can I rent a car for a month or longer in Santa Cruz? ### Where can I find a Santa Cruz car rental if I am younger than 25? ### What insurance should I choose for my car rental in Santa Cruz? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | - Experience new places with Expedia ### Car Rental Worldwide - [North America ](https://expedia.com/Destinations-In-North-America.d500001.Car-Rental-Destinations) - [Europe ](https://expedia.com/Destinations-In-Europe.d6022967.Car-Rental-Destinations) - [Caribbean ](https://expedia.com/Destinations-In-Caribbean.d6022969.Car-Rental-Destinations) - [Asia ](https://expedia.com/Destinations-In-Asia.d6023099.Car-Rental-Destinations) - [Australia - New Zealand and the South Pacific ](https://expedia.com/Destinations-In-Australia-New-Zealand-And-The-South-Pacific.d6023180.Car-Rental-Destinations) - [Mexico and Central America ](https://expedia.com/Destinations-In-Mexico-And-Central-America.d6023181.Car-Rental-Destinations) - [Middle East ](https://expedia.com/Destinations-In-Middle-East.d6023182.Car-Rental-Destinations) - [Africa ](https://expedia.com/Destinations-In-Africa.d6023185.Car-Rental-Destinations) ### Top Destinations in Santa Cruz - [Car rentals in Santa Cruz ](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide) - 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[Sportscar car rentals in Santa Cruz ](https://expedia.com/Sportscar-Car-Rentals-In-Santa-Cruz.d6297178-tSportscar.Car-Rental-Destination-Class) ### Expedia's Latest Trends Hotels - [Resorts & Hotels with Spas in La Paz](https://expedia.com/Destinations-In-La-Paz-Spa-Hotel.0-0-d6297090-tSpaHotel.Hotel-Filter-Destinations) - [La Guardia Hotels](https://expedia.com/La-Guardia-Hotels.d6347124.Travel-Guide-Hotels) - [Extended Stay Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels-Extended-Stay-Hotels.0-0-d6053940-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in La Paz](https://expedia.com/Destinations-In-La-Paz-Golf-Hotel.0-0-d6297090-tGolfHotel.Hotel-Filter-Destinations) - [Santa Cruz Hotels](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) - [Hotels with Hot Tubs in Cochabamba](https://expedia.com/Destinations-In-Cochabamba-Hotels-With-Hot-Tubs.0-0-d6297089-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Santa Cruz Casinos](https://expedia.com/Santa-Cruz-Hotels-Casino-Hotel.0-0-d6053940-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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